| 新型非甾体抗炎药—氟比洛芬制剂学研究进展 |
| 投稿时间：1998-07-25 点此下载全文 |
| 引用本文：钟延强,王春燕.新型非甾体抗炎药—氟比洛芬制剂学研究进展[J].药学实践杂志,1999,(2):97~101 |
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| 中文摘要:目的 介绍新型非甾体抗炎药-氟比洛芬制剂学的研究进展。方法 综述氟比洛芬的口腔控缓释制剂、透皮给药制剂、固体分散体、脂质体、环糊精包合物等新剂型、新工艺研究。结论 氟比洛芬是一种消炎镇痛作用强,毒副作用小的新一代非甾体抗炎药,普通片剂口服生物利用度低,可引起胃肠道反应等副作用,可以通过其控缓释制剂的剂型研究来弥补普通剂型的缺点,以发挥氟比洛芬这一新型药物的良好治疗效果。 |
| 中文关键词:氟比洛芬 控缓释制剂 生物利用度 制剂工艺 |
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| Researching development of flurbiprofen on pharmaceutics |
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| Abstract:OBJECTIVE The new dosageform(such as controlled and sustained release system,transdermal therapeutic product,solid dispersion,liposome,and cyclodextrin)of flurbiprofen were summarized. CONCLUSION Flurbiprofen is a new non-steroid anti-inflammation drugs which has strong anti-inflammation and antalgic function,but it has low bioavailability,and may bring gastric side effect.Preparing controlled and sustained release product can overcome it disadvantage,and play its good therapeutic function. |
| keywords:flurbiprofen controlled and sustained release system Bioavailabitity preparing technology |
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