褶合光谱法测定复方地塞米松滴眼液的含量
投稿时间:1998-07-15    点此下载全文
引用本文:史德懿,刘怡,张冬春.褶合光谱法测定复方地塞米松滴眼液的含量[J].药学实践杂志,1999,(1):37~40
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作者单位
史德懿 上海市第六人民医院 上海200233 
刘怡 上海医科大学药学院98届本科毕业生 上海200032 
张冬春 第二军医大学药学院 上海200433 
中文摘要:目的 建立不经分离同时测定地塞米松磷酸钠及干扰组分尼泊金乙酯含量的测定方法。方法 以蒸馏水为空白,采用褶合光谱法。结果 平均回收率为100.8%,99.39%;RSD为1.00%,0.61%。结论:本法方便准确,适用于紫外吸收有干扰的多组分制剂的常规分析。
中文关键词:复方地塞米松滴眼液  地塞米松磷酸钠  褶合光谱法  含量测定
 
Application of convolution spectrometry method for determination of compound dexamethasone sodium phosphate eye drops
Abstract:OBJECTIVE To simultaneous determine the main-component dexamethasone sodium phosphate and the interfering-component ethylparaben in compound dexamethasone sodium phosphate eye drops without separation. METHODS A convolution spectrometry method has been applied. RESULTS The average recoveris and relative standard deviation were 100.8%,10%;9939%,061%,respectively. CONCLUSION This method is convenient,accuracy and suitable for routine analysis of multicomponent preparation which has interference in ultraviolet spectrum.
keywords:compound dexamethasone sodium phosphate eye drops  dexamethasone sodium phosphate  convolution spectrum method  quantiative determination
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