甲苯磺酸托氟沙星胶囊溶出度测定方法的研究
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引用本文:袁国平,朱宝琬.甲苯磺酸托氟沙星胶囊溶出度测定方法的研究[J].药学实践杂志,1998,(3):157~159
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作者单位
袁国平 浙江省台州市药检所, 台州, 317000 
朱宝琬 浙江省台州市药检所, 台州, 317000 
中文摘要:本文报道用盐酸液(0.1mol/L)作溶剂,以转篮法测定甲苯磺酸托氟沙星胶囊的溶出度,按本实验测得的吸收系数(E1cm1%)为738计算主药的溶出量.本法简便、灵敏、准确,甲苯磷酸托氟沙星的平均回收率为100.2%,RSD=0.45%(n=8).
中文关键词:甲苯磺酸托氟沙星胶囊  溶出度  转篮法
 
Study of determination method of dissolution of tosufloxacin tosylate capsules
Abstract:A basket method was employed for determination of dissolution Of tosufloxacin tosylate capsules with hydrochloride acid solution (0.1mol/L) as medium. Calculated the dissolution of tesufloxacin tosylate,taking 738 as the value of A(1%, 1cm) that it was determinated by this test. This method was simple and accurate.The average recovery was 100.2%, RSD=0.45% (n=8).
keywords:tosufloxacin tosylate capsules  dissolution  basket method
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