| 控释氧氟沙星人工骨的质量控制及稳定性研究 |
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| 引用本文：景利,曾仁杰,刘明蓉,孙伟张,青磊,刘丰丰.控释氧氟沙星人工骨的质量控制及稳定性研究[J].药学实践杂志,1996,(4):225~227 |
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| 中文摘要:本文对控释氧氟沙星人工骨(简称OFLX-PHA-wax)的质量控制及稳定性进行了初步探讨。实验表明,用紫外分光光度法测定OFLX-PHA-wax的含量时,辅料不干扰氧氟沙星的测定。用FDA低温考查法、光照和加热稳定性试验考察了控释人工骨的稳定性。结果表明,其稳定性良好,使用期限可达2年以上。 |
| 中文关键词:氧氟沙星 控释人工骨 质量控制 稳定性 |
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| Study of quality Control and Stability of sustained release porous ofloxacin hydroxylapatite wax |
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| Abstract:Preliminary study of quality control and stability of sustained release porous ofloxacin hydroxylapatite wax was made. Experimental results showed that necessities did not interfere with determination of ofloxacin by uv. Each stability showed that there were no effects of light, heat and humidity on ofloxacin-porous hydroxylapatite wax(OFLX-PHA-wax). The results showed OFLX-PHA-wax could keep stable within two years. |
| keywords:ofloxacin sustained release porous hydroxylapatite wax quality control stability |
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