| 伊贝沙坦对慢性肾小球肾炎的肾脏保护作用 |
| 投稿时间：2004-02-23 点此下载全文 |
| 引用本文：汤俊达.伊贝沙坦对慢性肾小球肾炎的肾脏保护作用[J].药学实践杂志,2004,(4):211~212 |
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| 中文摘要:目的 研究伊贝沙坦对慢性肾小球肾炎患者尿蛋白的影响。方法 78例慢性肾炎病人接受伊贝沙坦(150mg,qd)治疗12周,分别测定治疗前、治疗6周和12周的24h尿蛋白定量。结果 经过治疗后,24h尿蛋白定量有显著下降,由治疗前的1.86g分别降至1.46g(6周)、1.18g(12周),P<0.01;治疗12周后与治疗6周后比较亦有显著下降(P<0.01)。结论 伊贝沙坦能够降低慢性肾炎患者尿蛋白,对肾脏具有保护作用。 |
| 中文关键词:伊贝沙坦 慢性肾小球肾炎 尿蛋白 |
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| Protective effect of irbesartan on renal in chronic glomerulonephritis |
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| Abstract:Objective To study the effect of irbesartan on decrease proteinuria excretion in chronic glomerulonephritis. Methods:78 cases of chronic glomerulonephritis have taken irbesartan tablets (150mg,qd) to treatment for 12 weeks, and all cases were examined the level of 24-hour-proteinuria before and after treatment 6 weeks,12 weeks. Results After treatment, the level of 24-hour-proteinuria was significantly decreased. The level of proteinuria decreased from 1.86g(before treatment) to 1.46g (after 6 weeks) and 1.18g (after 12 weeks),P<0.01,and the level in 12 weeks was much lower than in 6 weeks(P<0.01). Conclusion Irbesartan has significant effect on decrease proteinuria in chronic glomerulonephritis patients. |
| keywords:irbesartan chronic glomerulonephritis proteinuria |
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