| 盐酸洛美沙星乳膏剂的制备与质控 |
| 投稿时间：2001-03-26 点此下载全文 |
| 引用本文：梁雁.盐酸洛美沙星乳膏剂的制备与质控[J].药学实践杂志,2001,(4):219~221 |
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| 中文摘要:目的 制备盐酸洛美沙星乳膏剂,制定其质量控制标准。方法 采用紫外分光光度法中的对照品比较法测定盐酸洛美沙星乳膏剂中洛美沙星的含量,以甲醇为溶剂,测定波长287nm。 结果 测得盐酸洛美沙星乳膏剂中洛美沙星平均回收率为99.80%,RSD为0.27%(n=6),乳剂基质对测定无干扰。结论 该乳膏剂处方合理,制备工艺简单,含量测定操作简便,结果 准确。 |
| 中文关键词:盐酸洛美沙星 乳膏剂 制备 质量控制 |
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| Preparation and quality control of lomefloxacin hydrochloride cream |
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| Abstract:OBJECTIVE To prepare lomefloxacin hydrochloride cream, and establish the quality control standard. METHODS The content of lomefloxacin hydrochloride was determined with ultraviolet spectrophotometry. The solvent was methyl alcohol,the wavelength of determination was 287nm.RESULTS The average rate of lomefloxacin hydrochloride was 99.80%,and its RSD was 0.27%(n=6).The base of lomefloxacin hydrochloride cream didn't disturb this determination. CONCLUSION The technological process of lomefloxacin hydrochloride cream is easy. The method of content determination is simple and accurate. |
| keywords:lomefloxacin hydrochloride cream preparation quality control |
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