天然药物及活性化合物治疗心衰的研究进展
投稿时间:2023-06-09  修订日期:2023-11-01  点此下载全文
引用本文:吴欣怡,万静静,刘霞.天然药物及活性化合物治疗心衰的研究进展[J].药学实践杂志,2024,42(3):94~100
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作者单位E-mail
吴欣怡 海军军医大学药学系临床药学教研室, 上海 200433
河南大学药学院, 河南 开封 475004 
 
万静静 海军军医大学药学系临床药学教研室, 上海 200433  
刘霞 海军军医大学药学系临床药学教研室, 上海 200433 lxflying@aliyun.com 
中文摘要:心衰是各种心血管疾病的终末阶段,也是导致患者死亡的主要原因。长期以来,天然药物一直用于治疗心衰,且效果显著。对国家专利数据库中的中药复方专利数据进行数据挖掘,选出临床治疗心衰的常见中药,并对其含有的经典单一活性成分进行分析,为开发治疗心衰的天然药物提供理论依据。
中文关键词:心衰  天然药物  单体化合物  药理作用
 
Research progress on natural medicines and active compounds in the treatment of heart failure
Abstract:Heart failure is the terminal stage of various cardiovascular diseases and a leading cause of death. For a long time, natural medicines have been used to treat heart failure(HF) with remarkable effects. In this paper, the Traditional Chinese Medicine compound patents in the national patent database were mined, common Traditional Chinese Medicines for the clinical treatment of HF were selected, and the single active ingredient contained in them was analyzed, which provided some valuable tips for the development of drugs for the treatment of heart failure.
keywords:heart failure  natural medicine  monomer compounds  pharmacological action
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