| 醋蒸延胡索质量标准研究 |
| 投稿时间：2021-02-20 修订日期：2021-12-10 点此下载全文 |
| 引用本文：林源,魏雨辰,李晓东,卜其涛,许世辉,张成中.醋蒸延胡索质量标准研究[J].药学实践杂志,2022,40(1):57~61 |
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| 基金项目:安徽省食品药品监督管理局《安徽省中药饮片炮制规范》2019年版项目；海军军医大学本科生创新孵化基地项目（PH2019106）；温岭市科技局社会性项目（2020S0010021） |
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| 中文摘要:目的 制定符合《中国药典》要求的醋蒸延胡索质量标准，用于延胡索醋蒸炮制品种的生产、监督、流通及使用等各环节的质量控制。方法 参照《中国药典》（四部）2015年版通用检测方法分别对醋蒸延胡索的水分、总灰分、浸出物、主要有效成分含量进行测定。结果 依据中药质量标准制定指导原则及相关检测方法，根据实验数据，醋蒸延胡索呈不规则的圆形厚片，表面深黄色或黄褐色，有不规则细皱纹。质较硬，断面黄色或黄褐色，角质样，有蜡样光泽，微具醋香气，味苦。其水分含量不超过15.0%，总灰分不得超过4.0%，醇溶性浸出物不少于11.0%，按干燥品计算，含延胡索乙素（C21H25NO4）不少于0.050%。结论 实验所建立的醋蒸延胡索质量标准符合国家有关中药饮片质量标准制定要求，能够以标准的形式对醋蒸延胡索的质量进行控制。 |
| 中文关键词:醋蒸延胡索 鉴别 质量标准 |
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| Study on quality standard for vinegar-steamed Corydalis rhizoma |
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| Abstract:Objective To set up the quality standards for vinegar-steamed Corydalis rhizome, which can be used for the quality control of production, supervision, circulation and application of the steam processed Corydalis rhizoma with vinegar. Methods The moisture content, total ash, ethanol extract content and active ingredients of the steam processed Corydalis rhizoma with vinegar were determined according to the related assay method in Part IV of Chinese Pharmacopeia 2015. Results According to the guidelines from the traditional Chinese medicine quality standards and related testing methods, the moisture content of steam processed Corydalis rhizoma with vinegar should be less than 15.0%, the total ash content less than 4.0%, the ethanol extract content more than 11.0%, and the representative component of tetrahydropalmatine more than 0.05%. Conclusion The established process with this study for the quality standard of vinegar-steamed Corydalis rhizoma was conformed to the state requirements for traditional Chinese medicine. It can be used as a reference for the quality standard of vinegar-steamed Corydalis rhizoma. |
| keywords:vinegar-steamed Corydalis rhizoma identify quality standard |
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