| 多肽类化合物在颅脑创伤中的研究进展 |
| 投稿时间：2017-07-17 修订日期：2017-10-17 点此下载全文 |
| 引用本文：马凯源,章越凡,李铁军.多肽类化合物在颅脑创伤中的研究进展[J].药学实践杂志,2017,35(6):495~498,529 |
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| 基金项目:上海市卫生和计划生育委员会科研课题（201640404） |
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| 中文摘要:颅脑创伤每年在全球造成严重的伤亡，至今研究者们依然没有找到有效的临床治疗药物。肽类物质以其安全、易耐受等优势逐渐成为研究开发的热点。对多肽类化合物在颅脑创伤中的神经保护和抗炎作用进行综述。 |
| 中文关键词:颅脑创伤 肽类药物 神经保护 抗炎 |
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| Research progress of peptide compounds in traumatic brain injury |
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| Abstract:Traumatic brain injuries(TBI) have caused severe injuries and deaths all over the world, but so far researchers have not found an effective drug in treating TBI on clinic. However, peptides have gradually been in a hot research with its advantages which include safety and tolerance etc. The neuroprotective and anti-inflammatory effects of several peptide compounds in traumatic brain injury are reviewed in this paper. |
| keywords:traumatic brain injury peptides neuroprotection anti-inflammatory |
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