1例剖宫产瘢痕妊娠合并子宫卒中患者保守治疗用药分析
投稿时间:2016-05-04  修订日期:2016-09-01  点此下载全文
引用本文:吴越,王爱华,韩朝宏,冯欣.1例剖宫产瘢痕妊娠合并子宫卒中患者保守治疗用药分析[J].药学实践杂志,2016,34(6):552~555
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作者单位E-mail
吴越 四川省医学科学院·
四川省人民医院药学部, 四川 成都 610072
首都医科大学附属北京妇产医院药事部, 北京 100730 
 
王爱华 首都医科大学附属北京妇产医院药事部, 北京 100730 aihuacat@126.com 
韩朝宏 首都医科大学附属北京妇产医院药事部, 北京 100730  
冯欣 首都医科大学附属北京妇产医院药事部, 北京 100730  
中文摘要:目的 研究如何对剖宫产瘢痕妊娠(CSP)患者进行药物保守治疗。方法 1例CSP合并子宫卒中患者,在手术治疗无法开展的情况下,笔者探讨如何针对血清β-HCG>20 000 IU/L的患者制订药物保守治疗方案并预防产生毒副作用。结果 患者经2次子宫动脉栓塞+MTX50 mg子宫动脉灌注,3次MTX50 mg宫颈注射联合口服米非司酮保守治疗后,血清β-HCG转阴,无不良反应发生,保守治疗成功。结论 临床药师对CSP患者的药物保守治疗开展全程药学监护,对保障患者用药的安全、有效具有较大帮助和促进作用。
中文关键词:剖宫产瘢痕妊娠  子宫卒中  药物保守治疗  甲氨蝶呤  米非司酮
 
A case analysis of conservative treatment of a cesarean scar pregnancy combined with uterine apoplexy
Abstract:Objective To study the conservative treatment for cesarean scar pregnancy (CSP) with proper medications. Methods One case of CSP with uterine apoplexy was reported. Medication regimens were illustrated as the conservative treatments for the patient with β-HCG>20 000 IU/L, in whom surgery was contraindicated. Results After two times of uterine artery embolization and chemotherapy (MTX50 mg), followed by three times of MTX50 mg cervical injection combined with oral mifepristone, serum β-HCG dropped to normal level and no adverse reactions were observed. Conclusion Clinical pharmacists could strengthen the safety and effectiveness of rational drug use by participating in the integrated pharmacy care.
keywords:CSP  uterine apoplexy  conservative treatment  MTX  mifepristone
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