| 人血白蛋白在原发性肝癌肝切除术后的应用分析 |
| 投稿时间：2015-02-03 修订日期：2015-07-27 点此下载全文 |
| 引用本文：战旗,李悦悦,王晓俊,陈安妮,顾苏利,张国庆.人血白蛋白在原发性肝癌肝切除术后的应用分析[J].药学实践杂志,2015,33(5):463~466 |
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| 基金项目:上海市药学会医院药学科研基金(2012-YY-02-01) |
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| 中文摘要:目的 对东方肝胆外科医院原发性肝癌行肝切除术后使用人血白蛋白的情况进行合理性评价。 方法 回顾分析2012年6月至2013年6月期间150例原发性肝癌患者行肝切除术后应用人血白蛋白治疗的临床资料,比较患者术后应用人血白蛋白前后临床指标、生化指标,及人血白蛋白用药剂量相关因素分析,评价该院人血白蛋白的用药合理性。 结果 在统计的150份病历中,白蛋白总用量11 212.5 g(897瓶),总金额527 744元,占药品总费用的近20%,占住院总费用的近10%。患者在术后使用人血白蛋白后肝功能异常指标阳性率降低(P<0.05),人血白蛋白的使用剂量与患者用药前肝功能的Child-Pugh评分存在正相关(P<0.05)。 结论 该院原发性肝癌肝切除术后使用人血白蛋白较为合理,可达到预期的治疗效果。 |
| 中文关键词:人血白蛋白 肝切除术 肝功能 Child-Pugh评分 |
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| Analysis of application of human albumin after hepatectomy for primary liver cancer |
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| Abstract:Objective To assess the use of human albumin (ALB) after hepatectomy in hepatocellular carcinoma patients in our hospital. Methods 150 hospital medical records from June 2012 to June 2013 were analyzed, which used the human serum albumin during the perioperative period of hepatectomy at hepatocellular carcinoma (preoperative Child-Pugh A or B) retrospectively, the rationality of human blood albumin use was evaluated. Results Among the 150 medical records, the total application amount of albumin was 11 212.5 g (897 bottles), the total cost was 527,744 yuan, nearly 20 percent of total drug costs, accounting for nearly 10% of the total cost of hospitalization. By using human serum albumin after surgery, the patients' liver function was significantly improved(P<0.05), there was a positive correlation between the Child-Pugh score and dosage of human albumin (P<0.05). Conclusion The use of human serum albumin was rational during the perioperative period of hepatectomy in hepatocellular carcinoma patients in our hospital, which had achieved the desired therapeutic effect. |
| keywords:human serum albumin hepatectomy liver function Child-Pugh classification |
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