| 大蒜素对空肠弯曲杆菌抑菌作用的研究 |
| 投稿时间：2014-03-03 修订日期：2014-09-24 点此下载全文 |
| 引用本文：潘洪涛,杨宗兴,赵文萃,王艳萍,宋海艳,张琦.大蒜素对空肠弯曲杆菌抑菌作用的研究[J].药学实践杂志,2015,33(2):147~149,170 |
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| 中文摘要:目的 研究大蒜素对空肠弯曲杆菌的抑菌作用和强度。 方法 采用纸片扩散法(K-B法)测定抑菌圈直径;采用肉汤稀释法分别测定大蒜素、环丙沙星、红霉素对空肠弯曲杆菌的最低抑菌浓度(MIC),比较大蒜素、环丙沙星、红霉素的最低抑菌浓度及抑菌率。 结果 大蒜素(MIC为12.80 μg/ml,抑菌率90.40%)对空肠弯曲杆菌的抑菌作用较环丙沙星(MIC为20.48 μg/ml,抑菌率90.21%)和红霉素(MIC为35.84 μg/ml,抑菌率90.33%)更强。 结论 大蒜素对空肠弯曲杆菌具有抑菌作用。 |
| 中文关键词:大蒜素 环丙沙星 红霉素 最低抑菌浓度 抑菌率 |
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| Study on anti-microbial activity of allicin on campylobacter jejuni |
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| Abstract:Objective To study the anti-microbial activity and strength of allicin on Campylobacter jejuni. Methods Disc diffusion method (K-B) was used to determine the diameter of the bacteriostatic ring. The minimal inhibitory concentration (MIC) of allicin, ciprofloxacin and erythromycin were detected by constant broth dilution method, respectively.The minimal inhibitory concentrations and bacteriostatic rate of allicin,ciprofloxacin and erythromycin were compared. Results The anti-microbial activity on Campylobacter jejuni of allicin (MIC 12.8 μg/ml, bactetiostatic rate 90.40%) was better than that of ciprofloxacin (MIC 20.48 μg/ml, bactetiostatic rate 90.21%) and erythromycin (MIC 35.84 μg/ml, bactetiostatic rate 90.33%). Conclusion Allicin has anti-microbial activity on Campylobacter jejuni in vitro. |
| keywords:allicin ciprofloxacin erythromycin MIC bacteriostatic rate |
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