| 抗炎天然产物活性成分研究进展 |
| 投稿时间：2013-03-21 修订日期：2013-07-05 点此下载全文 |
| 引用本文：侯晓丽,孙铭学,高焕焕,肖凯.抗炎天然产物活性成分研究进展[J].药学实践杂志,2015,33(1):20~27 |
| 摘要点击次数: 1165 |
| 全文下载次数: 116 |
|
| 基金项目:上海市教委科研创新项目(12ZZ076);国家自然科学基金(20872179、30472141);国家科学技术重大项目(2013ZX09J13103-02C) |
|
| 中文摘要:炎症是具有血管系统的活体组织对各种损伤因子的刺激所发生的防御反应,在人体许多重大疾病的发生发展过程中起着极其重要的作用。临床上应用的抗炎药物主要有非甾体类抗炎药、甾体类抗炎药和中草药。由于现有的化学合成抗炎药物具有明显的不良反应,近年来人们越来越重视从天然产物中寻找、开发抗炎药物。以往的综述主要侧重于天然药物的抗炎机制,而对于天然药物中抗炎活性成分的总结却少有报道,笔者对近年来报道的具有抗炎作用的天然药物活性成分的研究进行综述,以期对进一步开发高效安全的抗炎药物提供参考。 |
| 中文关键词:天然产物 抗炎 免疫 |
| |
| Progress on anti-inflammatory natural products |
|
|
| Abstract:Inflammation is the defense response of the living tissues possessing vascular system to stimulations of various injury factors,which plays a vital role in the initiation and progression of many major diseases.Drugs used to treat inflammation in the clinical mainly include non-steroidal anti-inflammatory drugs (NSAIDs),steroidal anti-inflammatory drugs (SAIDs) and traditional Chinese medicine.As synthetic anti-inflammatory drugs used in clinical currently have obvious adverse reactions,more and more attention were paid to seek anti-inflammatory drugs from natural medicines.Reviews reported before mainly focus on anti-inflammation mechanism of natural medicine,however,there are few reports on the summary of anti-inflammatory natural products.Active natural products which were reported to possess anti-inflammatory effects in recent years were summarized in order to provide information for further study of anti-inflammatory drugs research. |
| keywords:natural products anti-inflammatory activities immunity |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
| 关闭 |
|
|
|
