| 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状 |
| 投稿时间：2013-07-21 修订日期：2013-12-02 点此下载全文 |
| 引用本文：李园园,于锋.哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J].药学实践杂志,2014,32(6):416~418,452 |
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| 中文摘要:目的 为哌拉西林钠-他唑巴坦钠的临床合理用药提供参考。方法 对哌拉西林钠-他唑巴坦钠的优选给药方案的药动/药效学研究、临床试验及具体实施情况进行综述。结果 哌拉西林钠-他唑巴坦钠的优选给药方案(延长输注或持续输注)可最大化地达到药效学目标,改善临床有效性。结论 需积极完善优化方案用于临床实践的策略。 |
| 中文关键词:哌拉西林钠-他唑巴坦钠 优选给药方案 延长输注 持续输注 |
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| Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium |
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| Abstract:Objective To offer reference to reasonable clinical use of piperacillin sodium sodium-tazobactam sodium.Methods We reviewed pharmacokinetic/ pharmacodynamic studies, clinical trails and implementation of piperacillin sodium-tazobactam sodium alternative dosing regimen in recent.Results The alternative dosing regimens, prolonged and continuous infusion, could maximise the likelihood of achieving desirable pharmacodynamic targets and improve clinical effectiveness.Conclusion It's needed to improve the strategies of alternative dosing regimens for clinical practice. |
| keywords:piperacillin sodium-tazobactam sodium alternative dosing regimen prolongrd infusion continuous infusion |
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