| 简述分析几种信号监测方法在药物不良事件中的应用 |
| 投稿时间：2011-11-24 修订日期：2012-05-16 点此下载全文 |
| 引用本文：代菲,舒丽芯,储藏,陈盛新,储文功.简述分析几种信号监测方法在药物不良事件中的应用[J].药学实践杂志,2012,30(5):380~383 |
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| 中文摘要:目的 分析国内外用于药物不良反应信号监测的几种监测算法。方法 运用文献分析法和系统分析法,阐述国内外针对药物不良反应信号的提取采取的一系列算法。结果 我国逐步开始引用不同的信号监测算法来发现药物不良反应(ADR)信号。结论 安全用药是当今和今后仍需要密切关注的问题,而药品安全性监测主要是通过对药品上市后不良信号监测来实现的。我们概括分析了目前国内外使用的有关信号监测的不同数据挖掘算法,为我国药品不良反应信号的处理提供参考,从而做好药物的安全警戒。 |
| 中文关键词:信号监测 药品安全性监测 数据挖掘方法 药品不良反应 |
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| Brief analysis the application of several signal monitoring methods in adverse drug events |
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| Abstract:Objective To analyze several adverse drug reaction monitoring methods in home and aboard.Methods Literature analysis and system analysis method were used to illustrate a series of calculation methods in signal extraction of adverse drug reaction. Results China had gradually begun to use different signal monitoring algorithms to detect adverse drug reaction (ADR) signals. Conclusion Medication safety issue still needed to be paid close attention to in current and future, and drug safety monitoring was mainly through the post-marketing adverse signal monitoring to achieve. Different data mining algorithms for relevant signal monitoring at home and in abroad were summarized, which would provide reference for our adverse drug reaction signal processing, and do good to the drug safety alert. |
| keywords:signal monitoring drug safety monitoring data mining algorithms adverse drug reaction |
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