| 复方川芎胶囊联合厄贝沙坦治疗糖尿病肾病患者的疗效观察 |
| 投稿时间：2011-12-08 修订日期：2011-12-18 点此下载全文 |
| 引用本文：陈海燕.复方川芎胶囊联合厄贝沙坦治疗糖尿病肾病患者的疗效观察[J].药学实践杂志,2012,30(1):55~57 |
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| 中文摘要:目的 观察复方川芎胶囊联合厄贝沙坦治疗糖尿病肾病的疗效。 方法 将323例糖尿病肾病患者随机分为两组,对照组162例给予厄贝沙坦,试验组在厄贝沙坦治疗基础上给予复方川芎胶囊。 结果 疗程结束后,试验组患者血清光抑素C、血肌酐水平、24 h尿蛋白量均下降,且组间比较差异有显著性。 结论 复方川芎胶囊联合厄贝沙坦应用可减少患者血清光抑素C、血肌酐水平,复方川芎胶囊联合厄贝沙坦疗效与单用厄贝沙坦相比,对糖尿病肾病患者有较好的肾脏保护作用。 |
| 中文关键词:复方川芎胶囊 厄贝沙坦 糖尿病肾病 |
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| Clinical efficacy of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy |
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| Abstract:Objective To investigate the effect of combination of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy. Methods 323 patients with diabetic nephropathy were randomly divided into 2 groups. Group I (Compound chuanqiong capsules plus Irbesartan group,n=161)and Group II (Irbesartan group,n=162). After 6 months follow-up,cystatin C,serum creatinine,24 h urine protein quantitate were respectively detected and compared before and after treatment. Results Compared to patients in the control group cystatin C,the patients'serum creatinine,24 h urine protein quantities decreased (P＜0.05). Conclusion The combination of Compound Chuanqiong capsules and irbesartan was more effective than irbesartan alone in the treatment of diabetic nephropathy. |
| keywords:Compound Chuanqiong capsules irbesartan diabetic nephropathy |
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