知母皂苷及其苷元的药理作用研究进展
投稿时间:2011-04-12  修订日期:2011-07-13  点此下载全文
引用本文:蔡飞,王维泓,高守红,陈万生.知母皂苷及其苷元的药理作用研究进展[J].药学实践杂志,2011,29(5):331~335
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作者单位E-mail
蔡飞 解放军广州军区机关门诊部药械科,广东 广州 510080  
王维泓 解放军广州军区机关门诊部药械科,广东 广州 510080  
高守红 第二军医大学附属长征医院药学部,上海 200003  
陈万生 第二军医大学附属长征医院药学部,上海 200003 chenwanshengsmmu@yahoo.com.cn 
中文摘要:知母皂苷及其苷元是临床常用中药材知母的最主要活性成分,具有广泛的生物活性和药理作用。研究表明,知母皂苷及其苷元具有防治老年痴呆症、保护脑缺血损伤、抗凝血、抗氧化、抗肿瘤、抗骨质疏松、抗炎、降血压、降血糖及降血脂等药理活性。本文对知母皂苷及其苷元的上述药理作用研究进展进行综述,为进一步开发利用提供参考。
中文关键词:知母皂苷  药理作用  研究进展
 
Advances in the pharmacological studies on timosaponins and their sapogenins
Abstract:Timosaponins and their sapogenins were the major active components from a commonly used Chinese herbal medicine, Anemarrhenae Rhizoma. Studies showed that they had a broad range of pharmacological effects such as improving senile dementia, preventing cerebral ischemia, anti-coagulated blood, anti-oxidant, anti-tumor, anti-osteoporosis, anti-inflammation, lowering blood pressure, lowering blood sugar and lowering blood fat. Recent advances in the above biological activities were reviewed in this paper.
keywords:timosaponin  pharmacological effects  advance
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