苦楝皮的化学成分研究
投稿时间:2011-06-03  修订日期:2011-06-28  点此下载全文
引用本文:颜滢,黄晨.苦楝皮的化学成分研究[J].药学实践杂志,2011,29(4):285~286,317
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作者单位
颜滢 衡阳市中心医院,湖南 衡阳 421001 
黄晨 衡阳市中心医院,湖南 衡阳 421001 
中文摘要:目的 研究驱虫药苦楝皮的化学成分。 方法 利用各种色谱方法对苦楝皮中的化学成分进行分离和纯化,并通过IR、MS、NMR等技术鉴定所得化合物的结构。 结果 苦楝皮中得到5个化合物,经鉴定为苦楝萜醇内酯(kulolactone,1)、苦楝萜酸甲酯(methyl kulonate,2)、salanin(3)、1-tigloyltrichilinin(4)及β-谷甾醇(5)。 结论 化合物4为一个新的柠檬苦素类化合物,命名为1-tigloyltrichilinin。
中文关键词:苦楝皮  化学成分  柠檬苦素
 
Study on the chemical constituents of Cortex Meliae
Abstract:Objective To study the chemical constituents of Cortex Meliae. Methods Chromatographic techniques were employed to isolate and purify the chemical constituents of Cortex Meliae. Structures of the chemical constituents were elucidated by methods of IR, MS and NMR. Results Five compounds were isolated and identified as kulolactone (1), methyl kulonate (2), salanin (3), 1-tigloyltrichilinin (4) and β-sitosterol (5), respectively. Conclusion Compound 4 was a new limonoid and named as 1-tigloyltrichilinin.
keywords:Cortex Meliae  chemical constituents  limonoid
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