| 肠康颗粒质量标准的研究 |
| 投稿时间：2010-09-26 修订日期：2011-01-19 点此下载全文 |
| 引用本文：刘璐,付聪.肠康颗粒质量标准的研究[J].药学实践杂志,2011,29(4):263~264,280 |
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| 中文摘要:目的 研究建立肠康颗粒的质量标准。 方法 采用薄层色谱法对肠康颗粒中黄连、乌梅进行定性鉴别;采用高效液相色谱法,测定方中君药黄连中盐酸小檗碱的含量。 结果 在薄层色谱中能检出黄连和乌梅;盐酸小檗碱在5.59~178.88 μg/ml范围内,浓度与峰面积线性关系良好(r＝0.999 9)。平均加样回收率为:103.3%(RSD=1.26%,n=6)。 结论 建立的方法对方中二味药材能准确、快速地进行定性、定量检测,可用于肠康颗粒的质量控制。 |
| 中文关键词:肠康颗粒 高效液相色谱法 薄层色谱法 黄连 乌梅 盐酸小檗碱 |
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| Study on quality control standard of changkang keli |
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| Abstract:Objective To establish the quality standard for changkang keli. Methods Coptidis rhizome , mume fructus were identified by TLC. The content of berberine hydrochloride was determined by HPLC. Results Coptidis rhizome, mume fructus could be identified by TLC. Berberine hydrochloride showed a good linear relationship at a rang of 5.59~178.88 μg/ml (r＝0.999 9). The average recovery (n=6) was 103.3% (RSD=1.26%). Conclusion The methods were accurate and quick, which could be used for the quality control of changkang keli. |
| keywords:changkang keli HPLC TLC coptidis rhizome mume fructus berberine hydrochloride |
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