550例药物不良反应报告分析
投稿时间:2008-10-28    点此下载全文
引用本文:丁雄芳.550例药物不良反应报告分析[J].药学实践杂志,2008,(6):472~475
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作者单位
丁雄芳 宁波市第一人民医院,浙江宁波315010 
中文摘要:目的:分析我院药物不良反应的特点,促进临床合理用药。方法:收集我院2007年1月1日~2008年8月31日的550份ADR报告。对引起ADR的药品种类、给药途径、ADR所致器官损害、ADR患者的不良反应史等进行统计分析。结果:550例ADR报告中,中老年患者占28.0%;抗生素ADR占61.64%;静脉滴注给药时发生ADR占70.0%。ADR的主要临床表现为皮疹、头晕、头痛及胃肠道反应。结论:应结合药物不良反应的特点和规律,严格把握用药适应证,加强用药监护,采取有针对性地监测和管理,尽量减少不良反应的发生。
中文关键词:药物不良反应(ADR)  合理用药
 
Analysis of 550 adverse drug reaction reports
Abstract:Objective:To analyze the characteristics of adverse drug reaction and promote rational clinical drug use.Methods: 550 ADR reports of our hospital during 1.1.2007 and 8.1.2008 has been collected.The categories and administration route of drugs that have caused ADR were statistically analyzed as well as the damaged organs caused by ADR and ADR patients'adverse drug reaction history.Results:Among the total 550 reports,the percentage of middle aged and elderly patients was 28.0%;the percentage of ADR caused by antibiotics was 61.64%;and that of ADR caused by intravenous drip was 70.0%.The major clinical manifestation of ADR were tetter,dizziness,headache and gastrointestinal reaction.Conclusion:based on the characteristics and discipline of ADR, the adapted symptoms of drugs should be strictly controlled,and supervision on drug use should be strengthened.Detection and management on ADR should be target-oriented taken to minimize the occurrence of ADR.
keywords:ADR  rational drug use
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