| ICP-MS分析参芪扶正注射液中14种微量元素的含量 |
| 投稿时间：2006-10-30 修订日期：2007-06-25 点此下载全文 |
| 引用本文：施丽飞,薛大方,李红,孙卫民,滕文锋.ICP-MS分析参芪扶正注射液中14种微量元素的含量[J].药学实践杂志,2008,(1):41~42 |
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| 基金项目:国家自然科学基金 |
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| 中文摘要:目的:通过测定中药制剂参芪扶正注射液中Cu、Zn、Mn、Se、Mo、Fe、Cr、Ni、V、Sn、Pb、Cd、Hg、As等14种微量元素的含量,探讨该中药注射液中元素的分布是否存在某种规律性。方法:微波消解法制备供试品,电感耦合等离子体-质谱(ICP-MS)法测定。结果:参芪扶正注射液中Cu、Fe、Zn、Cr、Se的相对含量较高,有毒元素Pb、Cd、Hg、As中As含量接近美国FAD药品与功能性食品要求标准,Pb、Cd、Hg含量均明显低于最高限量。结论:测定结果为探讨中药制剂中微量元素与抗肿瘤作用的关系提供有用的数据。 |
| 中文关键词:电感耦合等离子体-质谱 微量元素 中药制剂 |
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| Analysis of fourteen trace elements in Shenqifuzheng injcetion by ICP-MS |
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| Abstract:Objective:By determining fourteen trace elements including Cu,Zn,Mn,Se,Mo,Fe,Cr,Ni,V,Sn,Pb,Cd,Hg in Shenqifuzheng injection,a kind of traditional Chinese medicine ,the regularity of the distribution of these elements in the injection was discussed.Methods:The digested samples were determined by ICP-MS.Results:The concentrations of Cu,Fe,Zn,Cr and Se in Shenqifuzheng injection were higher than those of other elements. In four poisonous elements Pb,Cd,Hg and As, the concentration of As was close to the standard of FAD about drugs and functional foods. The concentrations of Pb、Cd and Hg were all obviously lower than the highest dose limit.Conclusion: The results provide useful data for discussing the relationship between trace elements in traditional Chinese medicine and the effect of tumor -treating. |
| keywords:Inductively coupled plasma mass spectrometry trace elements traditional Chinese medicine |
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