多效胃镜乳的处方改进及稳定性考察
投稿时间:2006-08-27    点此下载全文
引用本文:杨政,于西全,晏明.多效胃镜乳的处方改进及稳定性考察[J].药学实践杂志,2007,(1):31
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作者单位
杨政 福建省立医院药剂科,福建 福州 350001 
于西全 南京军区福州总院药剂科,福建 福州 350025 
晏明 第二军医大学,学员上海 200433 
中文摘要:目的:改进多效胃镜乳的处方,提高多效胃镜乳的稳定性,控制制剂的质量。方法:通过外观质量、显微镜检、离心试验、耐寒耐热试验、常温留样以及含量测定等为指标,考察不同的乳化剂对多效胃镜乳质量的影响,确定最优处方。结果:以0.8%司盘-80、1.6%西黄蓍胶和5%司盘-80、2%CMC-Na配制的多效胃镜乳,稳定性好。结论:改进后的多效胃镜乳处方可应用于制剂生产。
中文关键词:多效胃镜乳  处方改进  稳定性
 
Improvement and stability of multi-effect gastroscope emulsion
Abstract:Objective:To enhance the stability and control quality of the multi-effect gastroscope emulsion by improving the pre- scription of emulsion.Methods:The different prescriptiones of the multi-effect gastroscope emulsion were tested and evaluated by mi- croscopy,centrifugal experiment,cold-resistant/heat-resistant experiment,room temperature storage test as well as the content-determi- nation.Results:The emulsion with 0.8% span-80,1.6% tragacantha or with 5% span-80,2% CMC-Na has a good stability.Conclu- sion:The prescriptions of the multi-effect gastroscope emulsion can be applied to preparation production.
keywords:multi-effect gastroscope emulsion  prescription improvement  stability
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