鱼腥草注射液的细菌内毒素检查
投稿时间:2005-10-31    点此下载全文
引用本文:张建国.鱼腥草注射液的细菌内毒素检查[J].药学实践杂志,2006,(4):216~218
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作者单位
张建国 山东高密市人民医院,山东 高密 261500 
中文摘要:目的:建立鱼腥草注射液细菌内毒素检查法。方法:按《中国药典》2000年版二部收载的细菌内毒素检查法要求,确定样品最大有效稀释倍数,进行鱼腥草注射液细菌内毒素干扰试验。结果:鱼腥草注射液1:2倍稀释用λ为0.5EU/mL鲎试剂检查细菌内毒素存在抑制性干扰,1:4稀释用λ为0.25EU/mL鲎试剂可消除干扰因素,可有效检测该药细菌内毒素。结论:鲎试验法可用于鱼腥草注射液细菌内毒素检查,控制热原。
中文关键词:鱼腥草注射液  细菌内毒素  干扰试验  鲎试剂
 
Bacterial endotoxin test of Houttuynia injection
Abstract:Objective:To explore a bacterial endotoxin test for Houttuynia cordata injection. Methods:The bacterial endoloxin test was experimented according to the requirement of the second volum of China Pharmacopoeia,2000 edition. Results:The interference factors could be excluded in the Houttuynia cordata diluted to 4 times, the bacterial endotoxin could be determined effectively by 0. 25 EU/mL of TAL.Conclusion:The pyrogen notoxin in Houttuynia cordata injection can be determined by LLA.
keywords:Houttuynia cordata injection  bacterial endotoxin  interference experiment  tachypleus amebocyte lysale(TAL)
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