| 新型口服固体速释制剂—口腔崩解片的研究概况 |
| 投稿时间：2005-08-02 点此下载全文 |
| 引用本文：赵楠,汤真,李健,王艳萍,王伟东,谢华通,严小鹏.新型口服固体速释制剂—口腔崩解片的研究概况[J].药学实践杂志,2005,(6):326~330 |
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| 作者 | 单位 | | 赵楠 | 延边大学药学院, 吉林, 延吉, 133000 | | 汤真 | 中国人民解放军第208医院, 吉林, 长春, 130062 | | 李健 | 中国人民解放军第208医院, 吉林, 长春, 130062 | | 王艳萍 | 中国人民解放军第208医院, 吉林, 长春, 130062 | | 王伟东 | 中国人民解放军第208医院, 吉林, 长春, 130062 | | 谢华通 | 中国人民解放军第208医院, 吉林, 长春, 130062 | | 严小鹏 | 中国人民解放军第208医院, 吉林, 长春, 130062 |
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| 中文摘要:新型口服固体速释制剂—口腔崩解片以其在口腔内迅速崩解、起效快、生物利用度高、服用方便等特点受到了越来越多的药学工作者的关注,而且在很大程度上解决了老人、儿童等其他吞咽困难的病人服药难的问题.本文主要介绍了口腔崩解片的速崩机理、几种制备工艺及辅料,质量控制方法关键在于崩解时限和溶出度的检查,最后介绍了国内外已经上市的口腔崩解片的若干品种. |
| 中文关键词:口腔崩解片 崩解剂 速释制剂 |
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| A new solid dosage form:orally disintegrating tablets |
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| Abstract:A new oral solid dosage form of rapidly disintegrating tablets have attracted increasing attention by its novel characteristics, such as fast disintegration, rapid absorption, high bioavailability, convient taking and so on. The dosage form brings great benefits to children and elderly people, especially those who have difficulities in swallowing. This article mainly describes the fast disintegration mechanism of orally disintegrating tablets, some preparation methods and excipients. The key quality properties are disintegrating time and dissolution. Finally, the article introduces some products that have already come into market. |
| keywords:orally disintegrating tablets disintegrant dosage form of rapidly disintegrating |
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