| 三波长分光光度法测定复方双氢青蒿素片中双氢青蒿素的含量 |
| 投稿时间：2002-10-19 点此下载全文 |
| 引用本文：肖文中,詹利之,张美义,林燕芳.三波长分光光度法测定复方双氢青蒿素片中双氢青蒿素的含量[J].药学实践杂志,2003,(2):92~94 |
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| 中文摘要:目的 建立复方双氢青蒿素片中双氢青蒿素含量测定的方法。方法 主波长为250nm,基线波长1为271nm,基线波长2为301nm。结果 在6～30μg·mL-1,范围内线性良好,r=0.99992(n=10),平均回收率为101.7%,RSD为0.66%。结论 三波长分光光度法可不经分离,能消除甲氧苄啶和磷酸哌喹的干扰,从而直接测定复方制剂中双氢青蒿素的含量,该法操作简便、快捷、准确。 |
| 中文关键词:复方双氢青蒿素片 三波长分光光度法 双氢青蒿素 |
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| Determination of dihydroartemisinin of compound dihydroartemisinin tablets by tri-wavelength spectrophotosmetry |
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| Abstract:OBJECTIVE To establish the method of determination of content of compound dihydroartemisinin tablets. METHODS Detected at 250nm, with baseline wavelength 1 at 271nm and baseline wavelength 2 at 301nm.301 nm. RESULTS:Within 6-30μg·mL-1,DHA had a good linearity(r =0.99992,n=10).The average recoverty was 101.7%, with the RSD of 0.66%(n=9).CONCLUSION Tri-wavelength spectrophotosmetry can directly detected without the disturbance of trimethoprim and piperaquine phosphate,this method was simple,rapid,accurate. |
| keywords:compound dihydroartemisinin tablets trii-wavelength spectrophotometry dihydroartemisinin |
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