复方氯马斯汀霜制备和治疗季节性面部接触性皮炎的临床疗效
投稿时间:2000-07-13    点此下载全文
引用本文:黄贤琦,李冠勇,张华.复方氯马斯汀霜制备和治疗季节性面部接触性皮炎的临床疗效[J].药学实践杂志,2001,(2):73~74,72
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作者单位
黄贤琦 济南军区总医院, 济南 250031 
李冠勇 济南军区总医院, 济南 250031 
张华 济南军区总医院, 济南 250031 
中文摘要:目的 观察自制复方氯马斯汀霜治疗季节性面部接触性皮炎的临床疗效。方法 霜剂的制备采用o/w法。将94名门诊和住院患者随机分成两组,治疗组(51例)用复方氯马斯汀霜,对照组(43例)用康夫丽乐软膏,比较两组的疗效。结果 复方氯马斯汀霜组的治愈率和总有效率显著高于对照组(P <0.01,P <0.05)。结论 该制剂疗效确切,不良反应少,是治疗季节性面部接触性皮炎的理想药物,值得临床推广。
中文关键词:复方氯马斯汀霜  季节性面部接触性皮炎  临床疗效
 
Preparation of compound clemastine cream and its clinical efficacy for the treatment of seasonal contact dermatitis in the face
Abstract:OBJECTIVE To prepare compound clemastine cream(COC)and to evaluate its clinical efficacy for the treatment of seasonal contact dermatitis in the face.METHODS The preparation was obtained by traditional o/w method.94 outpatients and inpatients were randomly divided into active group(COC group)and control group(Kangfulire ointment group).RESULTS The healing rate and the total efficient rate were significantly higher than those of control group( p<0.01,p<0.05 ) CONCLUSION COC has reliable clinical efficacy and has little side effects,so it is one of the specific preparations for the treatment of contact dermatitis and it can be widely used in the clinics.
keywords:copound clemastine cream  seasonal contact dermatitis  clinical efficacy
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