| HPLC法测定盐酸美沙酮含量 |
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| 引用本文：林彩,代青,董慧,马文秀,刘松青.HPLC法测定盐酸美沙酮含量[J].药学实践杂志,1997,(5):299~301 |
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| 中文摘要:本文采用高效液相色谱法,以盐酸布比卡因为内标,检测波长220nm,在Symmetry-C18柱上,以己腈-磷酸二氢钾(pH2.5)(3862,V/V)为流动相,测定盐酸美沙酮及其口服液的含量。方法平均回收率为100.17%,日内及日间的RSD均<1%。方法简便、快速、准确。 |
| 中文关键词:盐酸美沙酮 盐酸美沙酮口服液 HPLC |
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| Determination of methadone hydrochloride by HPLC |
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| Abstract:To estab1ish a HPLC method for determining methadone hydrochloride and methadone hydrochloride oral solution.Using a Symmetry-C18 Chlumn,a mixture of acetoni trile-monobasic potassium phosphate(pH2.5)(38:62,V/V)as mobile phase and detected at 220nm bupivacaine hydrochloride was used as internal standard.The average recovery was 100.17%.The RSD for the inter inter and intra-day were all less than 1%.The method is simple,rapid and accurate. |
| keywords:methadone hydrochloride methadone hydrochloride oral solutinn HPLC |
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