| 1例少年肾移植患者环孢素的药动学分析及个体化给药 |
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| 引用本文：张显杰,倪福英,陆维艾.1例少年肾移植患者环孢素的药动学分析及个体化给药[J].药学实践杂志,1997,(3):151~153 |
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| 中文摘要:本文介绍1例少年肾移植患者术后按常规剂量口服环孢素A后血药浓度监测谷值偏低,根据患者的药代动力学参数及肝肾功能状态。应用微机软件制订个体给药方案,取得了满意的效果。 |
| 中文关键词:肾移植 环孢素A 药动学分析 个体化给药 |
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| Pharmacokinetic analysis and individual administration of cyclosporine for a juvenile renal transplant patients |
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| Abstract:It was reported that a juvenile renal transplant patients had a low cyclosporine whole blood concentration after normal administration.The pharmacokinetic parameters were: T1/2(Ke) = 3.15h, Tmax = 1.88h,Cmax=498.41ng·ml-1,AUC=3188.65(ng·ml-1)·h-1.Computer software was used to design the individual administration, that was 200mg, tid. Satisfactory effect was acquired. |
| keywords:renal transplant cyclosporine pharmacokinetic analysis individual administration |
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